Genomes and predicted metabolic pathways for thousands of organisms, together with a suite of software tools for analysis and visualization.
Pathway/Genome Databases (PGDBs) are generated by software that predict the metabolic pathways of completely sequenced organisms, predict which genes code for missing enzymes in metabolic pathways, and predict operons. BioCyc also integrates information from other bioinformatics databases, such as protein feature and Gene Ontology information from UniProt. The BioCyc website provides a suite of software tools for database searching and visualization, for omics data analysis, and for comparative genomics and comparative pathway questions.
The California Biobank Program (CBP) represents the combined biospecimen and data resources of two California Department of Public Health (CDPH) screening and monitoring programs, the California Birth Defects Monitoring Program (CBDMP) and the California Genetic Disease Screening Program (GDSP). GDSP administers both the Newborn Screening Program (NBS) and the Prenatal Screening Program (PNS), one of the largest and most comprehensive screening programs in the world.
The CBP has been mandated to make specimens and data available to researchers to identify risk factors for children's and women's diseases, develop and evaluate screening tests, develop and evaluate screening strategies, and develop and evaluate treatments.
A public database of annotated nucleotide sequences. Includes the Japanese Genotype-phenotype Archive (JGA), personal genotype and phenotype data from individuals who have signed consent agreements authorizing data release only for specific research uses.
A database for the bacterium Escherichia coli K-12 MG1655. The EcoCyc project performs literature-based curation of the entire genome, and of transcriptional regulation, transporters, and metabolic pathways.
ELIXIR (The European Life-Science Infrastructure for Biological Information Resources) is an intergovernmental organization that provides a single integrated infrastructure for bioinformatics data, software tools, and training materials.
A collection of freely available tools and data resources including BioModels (computational models), ChEMBL (bioactive compounds), Ensembl (genome browser), Expression Atlas (gene expression), GWAS Catalog (genome-wide association studies), Protein Data Bank (3D structures), and UniProt (protein sequences).
Portal of the SIB Swiss Institute of Bioinformatics to databases and software tools in proteomics, genomics, phylogeny, systems biology, evolution, population genetics, and transcriptomics. Formerly the Expert Protein Analysis System.
NCI-generated data from cancer genomic datasets, including The Cancer Genome Atlas (TCGA) and Therapeutically Applicable Research to Generate Effective Therapies (TARGET), supporting the elucidation of the molecular basis of cancer.
To browse the resource, no login is required. In order to save data and use specialized tools within this HGMD, users must first create a login. Collates genetic mutations that are responsible for human inherited disease. Includes links to relevant references from the scientific literature.
Database and gene expression pathway analysis software for data derived from 'omics experiments, such as RNA-seq, small RNA-seq, microarrays including miRNA and SNP, metabolomics, proteomics, and small-scale experiments.
Functional annotations relating to biological and chemical interactions, cellular phenotypes, and disease processes are referenced from the scientific literature.
A federally-supported collection of more than 40 databases and analysis tools for basic and applied research in molecular biology, including Assembly, Basic Local Alignment Search Tool (BLAST), BioProject, BioSample, Gene, Gene Expression Omnibus (GEO), Genome, Nucleotide, Protein, Structure, and the Sequence Read Archive (SRA).
Search biomedical literature citations from MEDLINE, life science journals, and online books. [1950 - present]
Access to citations from MEDLINE, PreMEDLINE, other journals in the field of medicine and life sciences, and links to NCBI's integrated molecular biology databases including nucleotide sequences, protein sequences, 3-D protein structure data, population study data sets, and assemblies of complete genomes in an integrated system.
Provides genomic, phenotypic and population-centric data for invertebrate vectors of human pathogens. Sponsored by NIAID-BRC (National Institute of Allergy and Infectious Diseases Bioinformatics Resource Center).