Library Guides: Optometry Residents: Clinical Trials &amp; More

ClinicalTrials.gov

ClinicalTrials.gov
Information on publicly and privately supported clinical studies on a wide range of diseases and conditions.
How to Search for Studies with Results in ClinicalTrials.gov
Find Studies With Results Posted to ClinicalTrials.gov, and Find Studies With Results Published in a Medical Journal.
Conditions by Category: Eye Diseases
Alphabetical list of eye disease clinical trials from Acanthamoeba Keratitis to Xerophthalmia.

PubMed: Use the Clinical Trial filter on the left sidebar after conducting a search.
Embase: Add AND 'clinical trial'/exp to your search. Example: presbyopia AND 'clinical trial'/exp.
WHO International Clinical Trials Registry Platform: Trial data from across the globe.
Grey Literature:
- Find clinical trial results on pharmaceutical companies' websites. Example: AstraZeneca-sponsored clinical trial data and results.
- FDA-approved medications: Drug Approval Packages, which consist of results and analyses from preclinical and all clinical phases, including integrated tolerability/safety analyses.
- Also check institutional websites, conference proceedings, and elsewhere; see Beyond PubMed: Searching the "Grey Literature" for Clinical Trial Results (by L Citrome: Innov Clin Neurosci. 2014 Jul;11(7-8):42-6.)
Unfortunately, many clinical trial result are never published. See Linking ClinicalTrials.gov and PubMed to Track Results of Interventional Human Clinical Trials (by V Huser and JJ Cimino: PLoS One. 2013; 8(7): e68409.)

50 Studies Every Ophthalmologist Should Know
(Penman, Crowder, Watkins: 2020). Summaries of the most important and clinically relevant studies of the past forty years. Emphasis has been placed on landmark studies, that changed thinking and practice in the field. Most are randomized controlled trials that have helped shape current ophthalmology practice guidelines.
Age-Related Eye Disease Studies (AREDS/AREDS2)
AREDS and AREDS2 are major clinical trials sponsored by the National Eye Institute. The AREDS studies were designed to learn more about the natural history and risk factors of age-related macular degeneration and cataract and to evaluate the effect of vitamins on the progression of these eye diseases.
Landmark Trials in Ophthalmology
Disease entity, study groups, results, and primary conclusion of major clinical trials in Ophthalmology. PubMed references are available for each. From eyeguru.org.
Pivotal Trials in Ophthalmology: A Guide for Trainees
A comprehensive and accessible overview of landmark trials in the different subspecialties of ophthalmology. The text is subdivided by subspecialty, with each chapter authored by both a trainee and an expert in the field. A selection of pivotal research studies that have shaped how practitioners diagnose, manage, and treat disease are reviewed in chronological order.